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何玉龙 性 别:男 出生年月:1979年9 月 职 称:副教授 硕导 所 在 系: 生物制药 办 公 室: 6-419 电 话:0571-86843193 电子邮件:heyulong2003@163.com |
主要学习与工作经历
1. 1999.09-2003.06 内蒙古民族大学 本科;
2. 2003.09-2006.06 西北农林科技大学 硕士;
3. 2006.09-2011.06 西北农林科技大学 博士;
4. 2008.12-2010.09美国UT Health Science Center at San Antonio(UTHSCSA) 访问学者;
5. 2011.07-2016.02 宁夏大学 生命科学学院/西部特色生物资源保护与利用教育部重点实验室 教学科研;
6. 2016.03-至今 太阳成集团tyc151cc 生命科学与医药公司 教学科研。
主要研究方向
动物疫苗及诊断试剂开发;
免疫学技术研究。
获奖与荣誉
2012年度获宁夏自治区“全职引进优秀博士”称号;
2020年度浙江省高校产学研联盟“博士入企”考核优秀;
2023年度获太阳成集团tyc151cc“三育人”先进个人称号;
2023年度太阳成集团tyc151cc“校科技贡献奖”;
2023年度第十五届中国商业联合会服务业科技创新一等奖(4/6)。
主要学术及社会兼职
浙江省畜牧兽医学会理事、浙江省免疫学会动物免疫专业委员会委员、浙江省农业农村厅人畜共患病防控专家;
中国细胞生物学学会会员、中国生物化学与分子生物学会会员、中国农业生物技术学会动物生物技术分会会员、浙江省农学会会员。
科研教学项目
1、主持及主持结题科研项目
主持或主持结题国家自然科学基金项目1项、留学回国人员创新创业项目1项、省(宁夏自治区)自然科学基金项目1项、省公益技术应用研究项目2项、省“领雁”研发攻关计划项目子课题1项、新疆建设兵团科技计划项目子课题1项、省 “三农九方”农业科技协作计划项目子课题1项、省高校生物学重中之重(一级)学科带头人培养专项1项及企业委托横向课题8项。
2、参与科研项目
作为科研骨干参于国家“973”计划子课题、“973”前期研究专项和浙江省重点研发计划项目5项、以第二或第三参与人参与国家自然科学基金5项等。
3、教学改革项目
主持结题校级《免疫学》优质课程建设项目1项、校级《生物制药工艺学》课程思政示范建设项目1项;以第二申请人申请获批《基因工程技术制备门冬酰胺酶(冻干粉针)工艺》国家级虚拟仿真实验教学项目1项。
学术论文(第一作者和通讯作者)
1. Yulong He, Yuehong Wu, Anuja Mishra, Victor Acha, Thomas Andrews, Peter J. Hornsby*. Biosensor technology in aging research and age-related diseases. Ageing Research Reviews. 2012,11(1):1-9(医学1区TOP)(SCI)
2. Yulong He, Yuehong Wu, Zhigang Lan, Yonggang Liu, Yong Zhang*. Molecular analysis of the first intron in the bovine myostatin gene, Molecular biology reports. 2011,38(7):4643-9. (SCI)
3. Yulong He, Yuehong Wu, Xiaoning He, Fengjun Liu, Xiaoying He, Yong Zhang*. An immortalized goat mammary epithelial cell line induced with human telomerase reverse transcriptase (hTERT) gene transfer, Theriogenology. 2009,71(9):1417-24.(SCI)
4. Yulong He, Yuehong Wu, Fusheng Quan, Yonggang Liu, Yong Zhang*. Comparative analysis of sequence of myostatin gene and promoter in Qinchuan and Red Angus cattle. Genetics and Molecular Research. 2013,12(3):3398-3406. (SCI)
5. Yuehong Wu, Jianhong Shu, Chengwen He, Min Li, Yujiong Wang, Wenbin Ou, Yulong He(通讯作者). ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset iPS cells by suppressing expression and activity of Caspase-3. Theriogenology. 2016, 85(2):302-314. (SCI)
6. Danping Hong, Jiongyan Ding, Ouyang Li, Quan He, Minxia Ke, Mengyi Zhu, Lili Liu, Wen-Bin Ou, Yulong He* and Yuehong Wu*. Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection. Stem Cell Research & Therapy, 2018, 9(1):49. (SCI)
7. Minxia Ke, Quan He, Danping Hong, Ouyang Li, Mengyi Zhu, Wen‑Bin Ou, Yulong He*, Yuehong Wu*. Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway. International Journal of Molecular Medicine, 2018, 42(1):131-140. (SCI)
8. Yi Yang, Xiaokang Liu, Ting Wu, Wenping Zhang, Jianhong Shu*, Yulong He*, ShaoJun Tang. Quercetin attenuates AZT-induced neuroinflammation in the CNS. Scientific Reports, 2018, 8(1):6194. (SCI)
9. Yu Tao, Jianhong Shu, Jian Chen, Yuehong Wu*, Yulong He*. A concise review of vaccines against Mycoplasma hyopneumoniae. Research in Veterinary Science, 2019,123:144-152. (SCI)
10. Rui Yang, Yu Tao, Gaojian Li, Jian Chen, Jianhong Shu* and Yulong He*. Immunoenhancement of recombinant Neisseria meningitides PorB protein on porcine circovirus type 2 and Mycoplasma hyopneumoniae genetically engineered vaccines. Protein & Peptide Letters, 2019, 26(10): 776 - 784. (SCI)
11. Yu Tao, Gaojian Li, Wenqian Zheng, Jianhong Shu, Jian Chen, Fang Yang, Yuehong Wu*, and Yulong He*. Development of a Combined Genetic Engineering Vaccine for Porcine Circovirus Type 2 and Mycoplasma Hyopneumoniae by a Baculovirus Expression System. International Journal of Molecular Sciences. 2019, 20, 4425. (SCI)
12. Gaojian Li, Enoch Obeng, Jinqi Shu, Jianhong Shu, Jian Chen, Yuehong Wu* and Yulong He*. Genomic variability and post-translational protein processing enhance the immune evasion of Mycoplasma hyopneumoniae and its interaction with the porcine immune system. Frontiers in Immunology. 2020, 08, DOI: 10.3389/fimmu.2020.510943. (SCI)
13. Yu Tao, Rui Yang, Jianhong Shu, Wenqian Zheng, Jian Chen, Yuehong Wu and Yulong He*. Immune responses induced by a combined vaccination with a recombinant chimera of Mycoplasma hyopneumoniae antigens and capsid virus-like particles of porcine circovirus type 2, BMC Veterinary Research, 2020, 16(1):342.(SCI)
14. Gaojian Li, Jinqi Shu, Jing Jin, Jianhong Shu, Huapeng Feng, Jian Chen and Yulong He*. Development of a Multi-Epitope Vaccine for Mycoplasma hyopneumoniae and Evaluation of Its Immune Responses in Mice and Piglets. International Journal of Molecular Sciences. 2022, 23(14):7899. (SCI)
15. Bin Jiang, Ying Zhang, Gaojian Li, Yanping Quan, Jianhong Shu, Huapeng Feng, Yulong He*. Research progress on immune evasion of Mycoplasma hyopneumoniae. Microorganisms. 2024, 12(7): 1439. (SCI)
16. Jinqi Shu, Gaojian Li, Jianhong Shu, Huapeng Feng, Yulong He*. CD40 Ligand Potentiates Immunogenecity of Mycoplasma pneumoniae Subunit Vaccine Candidate in a Murine Model. Current Issues in Molecular Biology. 2025, 47(1): 37. (SCI)
17. Yu Duan, Yue Hao, Huapeng Feng, Jianhong Shu* and Yulong He*. Research progress on Haemophilus parasuis vaccines. Front. Vet. Sci. 2025, 12:1492144. (SCI)
授权发明专利
1. 何玉龙, 陶宇, 舒建洪, 陈健, 吴月红, 杨芳. 猪支原体肺炎和猪圆环病毒2型重组蛋白及制备二联疫苗. 专利号:ZL201811179696.3.
2. 何玉龙, 陶宇, 舒建洪, 陈健, 杨芳, 童夏霞, 盛敏成. 猪支原体肺炎和猪圆环病毒二联基因工程疫苗制备方法. 专利号:ZL201910200702.7.
3. 何玉龙, 李高建, 舒建洪, 舒金琪, 查银河. 一种基于反向疫苗学技术的猪肺炎支原体多表位基因工程亚单位疫苗的制备方法及其应用. ZL202111664581.5.
参编教材情况
参编高等教育出版社《免疫学原理与技术》(第一版)、(第二版)新形态教材和《新药药理学》数字课程各1项。